Secuelas comunes en el síndrome post-covid-19: revisión sistemática.

Autores/as

DOI:

https://doi.org/10.56048/MQR20225.7.3.2023.4332-4348

Palabras clave:

COVID-19, Sociodemográfica, síndrome post-covid19, SARS-CoV-2

Resumen

La infección por el coronavirus 2 del síndrome respiratorio agudo severo (SARS-CoV-2) fue responsable de la pandemia de la enfermedad por coronavirus 2019 (COVID-19) que provoco millones de muertes y una gran presión sobre los sistemas de salud de todo el mundo. La mayoría de los pacientes se recuperaron espontáneamente o después del manejo de la fase aguda, sin embargo, algunos presentaron complicaciones a largo plazo de COVID-19, incluida una gran variedad de síntomas, definidos como síndrome post-COVID-19. Se realizó una revisión sistemática de la literatura, siguiendo criterios de exclusión y sistematización. Se hicieron búsquedas de estudios aleatorios (ECA) en las bases de datos científicas tales como: PubMed, SciELO, Elsevier, Google Scholar, Redalyc, Springer. Después de examinar 75 estudios, un total de 50 estudios fueron elegibles. Las secuelas notificadas con mayor frecuencia fueron fatiga, disnea, trastorno del sueño y dificultad para concentrarse. En conclusión, se encontró que una gran proporción de pacientes experimentan síndrome de post-covid-19 3 a 12 meses después de la recuperación de la fase aguda de COVID-19.

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    Cited

    DOI: 10.56048DOI

Biografía del autor/a

Briana Zambrano-Pico, Universidad Estatal Del Sur De Manabí

Estudiante de la carrera de Laboratorio Clínico

Ana Arteaga-Zambrano, Universidad Estatal Del Sur De Manabí

Estudiante de la carrera de Laboratorio Clínico

Evelyn Moreira-Mendoza, Universidad Estatal Del Sur De Manabí

Estudiante de la carrera de Laboratorio Clínico

Jazmín Elena Castro-Jalca, Universidad Estatal Del Sur De Manabí

Docente Tutor del área de Laboratorio clínico

Citas

Ena J, Wenzel RP. Un nuevo coronavirus emerge. Rev Clínica Española [Internet]. 2020 [cited 2023 Jul 1];220(2):115–6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130265/

WHO. World Health Organization. Disease outbreak news. 2020 [cited 2022 Mar 11]. p. 3–5 Pneumonia of unknown cause – China. Available from: https://www.who.int/emergencies/disease-outbreak-news/item/2020-DON229

World Health Organization (WHO). WHO. 2020 [cited 2022 Jun 29]. WHO Director-General’s opening remarks at the Mission briefing on COVID-19 - 16 April 2020. Available from: https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-mission-briefing-on-covid-19---28-may-2020

Ruiz-Bravo A, Jiménez-Valera M, Ruiz-Bravo A, Jiménez-Valera M. SARS-CoV-2 y pandemia de síndrome respiratorio agudo (COVID-19). Ars Pharm [Internet]. 2020 [cited 2023 Jul 1];61(2):63–79. Available from: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942020000200001&lng=es&nrm=iso&tlng=es

Morales AGA, Herrera FVE, Morales AGA, Herrera FVE. Secuelas del COVID-19, un desafío de la salud pública: Revisión bibliográfica. Vive Rev Salud [Internet]. 2022 Dec 21 [cited 2023 Jul 1];5(15):889–908. Available from: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S2664-32432022000300889&lng=es&nrm=iso&tlng=es

Organización Mundial de la Salud(OMS). Brote de enfermedad por coronavirus (COVID-19) [Internet]. 2023. Available from: https://www.paho.org/es/temas/coronavirus/brote-enfermedad-por-coronavirus-covid-19

Statista Research Department. Coronavirus en Latinoamérica: países con más casos [Internet]. 2023 [cited 2023 Jan 30]. p. 1–5. Available from: https://es.statista.com/estadisticas/1105121/numero-casos-covid-19-america-latina-caribe-pais/

Ministerio de Salud Publica. Situación coronavirus Covid-19 [Internet]. 2023. Available from: https://www.salud.gob.ec/actualizacion-de-casos-de-coronavirus-en-ecuador/

Mahmud R, Rahman MM, Rassel MA, Monayem FB, Sayeed SKJB, Islam MS, et al. Post-COVID-19 syndrome among symptomatic COVID-19 patients: A prospective cohort study in a tertiary care center of Bangladesh. Zivkovic AR, editor. PLoS One [Internet]. 2021 Apr 8;16(4):e0249644. Available from: https://dx.plos.org/10.1371/journal.pone.0249644

Shah S, Bhattarai SR, Basnet K, Adhikari YR, Adhikari TB, Bhatta N, et al. Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. PLoS One [Internet]. 2022;17(8):e0272636. Available from: https://doi.org/10.1371/journal.pone.0272636

Ortega Martinez RA. Caracterización de la evolución del Síndrome Post COVID-19 en Cochabamba Bolivia, 2020-2021. Rev Peru Ciencias la Salud [Internet]. 2023 Jul 12 [cited 2023 Aug 15];5(2):415–415. Available from: http://revistas.udh.edu.pe/index.php/RPCS/article/view/415e

Romo Á, Terán C, Gavilanes M. Incidencia y características clínicas del síndrome post COVID-19 en la población adulta de Tungurahua, marzo 2020-enero 2022. Rev del Grup Investig en Comunidad y Salud [Internet]. 2022 [cited 2023 Aug 15];7(3):10–20. Available from: https://dialnet.unirioja.es/servlet/articulo?codigo=8632927&info=resumen&idioma=ENG

Otano M, Mejía A, Avilés M. Vista de Principios bioéticos y su aplicación en las investigaciones médico-científicas. Cienc Ecuador [Internet]. 2021;3(3):9–16. Available from: https://doi.org/10.23936/rce.v3i3.27

Klinkhammer S, Horn J, Duits AA, Visser-Meily JMA, Verwijk E, Slooter AJC, et al. Neurological and (neuro)psychological sequelae in intensive care and general ward COVID-19 survivors. Eur J Neurol [Internet]. 2023 Jul 1 [cited 2023 Jul 26];30(7):1880–90. Available from: https://doi.org/10.1111/ene.15812

Ertesvåg NU, Iversen A, Blomberg B, Özgümüş T, Rijal P, Fjelltveit EB, et al. Post COVID-19 condition after delta infection and omicron reinfection in children and adolescents. eBioMedicine [Internet]. 2023;92(4):104599. Available from: https://doi.org/10.1016/j.ebiom.2023.104599

Wahlgren C, Forsberg G, Divanoglou A, Östholm Balkhed Å, Niward K, Berg S, et al. Two-year follow-up of patients with post-COVID-19 condition in Sweden: a prospective cohort study. Lancet Reg Heal - Eur [Internet]. 2023;28(14):100595. Available from: https://doi.org/10.1016/j.lanepe.2023.100595

Buonsenso D, Munblit D, Pazukhina E, Ricchiuto A, Sinatti D, Zona M, et al. Post-COVID Condition in Adults and Children Living in the Same Household in Italy: A Prospective Cohort Study Using the ISARIC Global Follow-Up Protocol. Front Pediatr. 2022 Apr 21;10:834875.

Halpin SJ, McIvor C, Whyatt G, Adams A, Harvey O, McLean L, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol [Internet]. 2021 Feb 1 [cited 2023 Jul 25];93(2):1013–22. Available from: https://doi.org/10.1002/jmv.26368

Van den Borst B, Peters JB, Brink M, Schoon Y, Bleeker-Rovers CP, Schers H, et al. Comprehensive Health Assessment 3 Months After Recovery From Acute Coronavirus Disease 2019 (COVID-19). Clin Infect Dis [Internet]. 2021 Sep 1;73(5):e1089–98. Available from: https://doi.org/10.1093/cid/ciaa1750

Goërtz Y, Herck M Van, Delbressine JM, Vaes AW, Meys R, Machado FVC, et al. Persistent symptoms 3 months after a SARS-CoV-2 infection: the post-COVID-19 syndrome? ERJ Open Res [Internet]. 2020 Oct 1;6(4):542–2020. Available from: http://openres.ersjournals.com/content/6/4/00542-2020.abstract

Carfì A, Bernabei R, Landi F. Persistent Symptoms in Patients After Acute COVID-19. JAMA [Internet]. 2020 Aug 11;324(6):603–5. Available from: https://doi.org/10.1001/jama.2020.12603

Shukla AK, Atal S, Banerjee A, Jhaj R, Balakrishnan S, Chugh PK, et al. An observational multi-centric COVID-19 sequelae study among health care workers. Lancet Reg Heal - Southeast Asia [Internet]. 2023;10:100129. Available from: https://doi.org/10.1016/j.lansea.2022.100129

Iqbal A, Iqbal K, Ali SA, Azim D, Farid E, Baig MD, et al. The COVID-19 Sequelae: A Cross-Sectional Evaluation of Post-recovery Symptoms and the Need for Rehabilitation of COVID-19 Survivors. Cureus [Internet]. 2021 Feb 2 [cited 2023 Jul 26];13(2). Available from: doi:10.7759/cureus.13080

Xiong Q, Xu M, Li J, Liu Y, Zhang J, Xu Y, et al. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infect [Internet]. 2021 Jan;27(1):89–95. Available from: https://doi.org/10.1016/j.cmi.2020.09.023

Azizi A, Achak D, Saad E, Hilali A, Youlyouz-Marfak I, Marfak A. Post-COVID-19 mental health and its associated factors at 3-months after discharge: A case-control study. Clin Epidemiol Glob Heal [Internet]. 2022 Sep;17:101141. Available from: https://linkinghub.elsevier.com/retrieve/pii/S221339842200183X

Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract [Internet]. 2021 Mar 1 [cited 2023 Jul 27];75(3):e13746. Available from: https://doi.org/10.1111/ijcp.13746

Mancilla-Ceballos R, Milne KM, Guenette JA, Cortes-Telles A. Inflammation associated with lung function abnormalities in COVID-19 survivors. BMC Pulm Med [Internet]. 2023;23(1):235. Available from: https://doi.org/10.1186/s12890-023-02521-5

Acharya S, Akram A, Kodali A, Donovan S, Gupta SS, Kodali L. Post COVID-19 pulmonary complications in outpatient setting: Insights from a cross-sectional study in a rural academic hospital. Am J Emerg Med [Internet]. 2023;68:124–6. Available from: https://doi.org/10.1016/j.ajem.2023.03.031

Llanga Vargas EF, Guacho Tixi ME, Robalino Valdiviezo MP. Secuelas respiratorias síndrome post- COVID-19 en adultos mayores de la provincia de Chimborazo. La Cienc al Serv la Salud y la Nutr [Internet]. 2023 Mar 2 [cited 2023 Jul 26];14(1):16–24. Available from: http://revistas.espoch.edu.ec/index.php/cssn/article/view/779/800

Del Socorro Goicochea Ríos E, Córdova Paz Soldán OM, Gómez Goicochea NI, Vicuña Villacorta J. Secuelas post infección por COVID 19 en pacientes del Hospital I Florencia de Mora. Trujillo - Perú [Internet]. Vol. 22, Revista de la Facultad de Medicina Humana. scielo; 2022. p. 754–64. Available from: http://dx.doi.org/10.25176/rfmh.v22i4.5045

Núñez-Cortés R, Leyton-Quezada F, Pino MB, Costa-Costa M, Torres-Castro R. Secuelas físicas y emocionales en pacientes post hospitalización por COVID-19. Rev Med Chil [Internet]. 2021;149(7):1031–5. Available from: http://dx.doi.org/10.4067/s0034-98872021000701031

Soriano JB, Murthy S, Marshall JC, Relan P, Diaz J V. A clinical case definition of post-COVID-19 condition by a Delphi consensus. Lancet Infect Dis [Internet]. 2022;22(4):e102–7. Available from: https://doi.org/10.1016/S1473-3099(21)00703-9

Ballering A V, van Zon SKR, olde Hartman TC, Rosmalen JGM. Persistence of somatic symptoms after COVID-19 in the Netherlands: an observational cohort study. Lancet. 2022 Aug;400(10350):452–61.

Al-Aly Z, Xie Y, Bowe B. High-dimensional characterization of post-acute sequelae of COVID-19. Nature [Internet]. 2021;594(7862):259–64. Available from: https://doi.org/10.1038/s41586-021-03553-9

Zahin Amin-Chowdhury Bs, Ross J Harris P, Felicity Aiano Ms, Maria Zavala Ms, Marta Bertran Ms, Ray Borrow P, et al. Characterising post-COVID syndrome more than 6 months after acute infection in adults; prospective longitudinal cohort study, England. medRxiv [Internet]. 2021 Apr 16 [cited 2023 Jul 28];12(3):120–9. Available from: https://doi.org/10.1101/2021.03.18.21253633

Daher A, Balfanz P, Cornelissen C, Müller A, Bergs I, Marx N, et al. Follow up of patients with severe coronavirus disease 2019 (COVID-19): Pulmonary and extrapulmonary disease sequelae. Respir Med [Internet]. 2020;174:106197. Available from: https://doi.org/10.1016/j.rmed.2020.106197

Zhao Y miao, Shang Y min, Song W bin, Li Q quan, Xie H, Xu Q fu, et al. Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. EClinicalMedicine [Internet]. 2020;25:100463. Available from: https://doi.org/10.1016/j.eclinm.2020.100463

Cassar MP, Tunnicliffe EM, Petousi N, Lewandowski AJ, Xie C, Mahmod M, et al. Symptom Persistence Despite Improvement in Cardiopulmonary Health – Insights from longitudinal CMR, CPET and lung function testing post-COVID-19. eClinicalMedicine [Internet]. 2021;41:101159. Available from: https://doi.org/10.1016/j.eclinm.2021.101159

Logue JK, Franko NM, McCulloch DJ, McDonald D, Magedson A, Wolf CR, et al. Sequelae in Adults at 6 Months After COVID-19 Infection. JAMA Netw Open [Internet]. 2021 Feb 19;4(2):e210830–e210830. Available from: https://doi.org/10.1001/jamanetworkopen.2021.0830

Nehme M, Braillard O, Chappuis F, Courvoisier DS, Guessous I. Prevalence of symptoms more than seven months after diagnosis of symptomatic covid-19 in an outpatient setting. Ann Intern Med [Internet]. 2021 Sep 1 [cited 2023 Jul 27];174(9):1252–60. Available from: https://doi.org/10.7326/M21-0878

Fang X, Ming C, Cen Y, Lin H, Zhan K, Yang S, et al. Post-sequelae one year after hospital discharge among older COVID-19 patients: A multi-center prospective cohort study. J Infect [Internet]. 2022;84(2):179–86. Available from: https://doi.org/10.1016/j.jinf.2021.12.005

Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet (London, England) [Internet]. 2021 Jan;397(10270):220–32. Available from: https://doi.org/10.1016/s0140-6736(20)32656-8

Ngasa SN, Tchouda LAS, Abanda C, Ngasa NC, Sanji EW, Dingana TN, et al. Prevalence and factors associated with anxiety and depression amongst hospitalised COVID-19 patients in Laquintinie Hospital Douala, Cameroon. PLoS One [Internet]. 2021;16(12):e0260819. Available from: https://doi.org/10.1371/journal.pone.0260819

Guo Q, Zheng Y, Shi J, Wang J, Li G, Li C, et al. Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: A mixed-method study. Brain Behav Immun. 2020 Aug;88:17–27.

Talhari C, Criado PR, Castro CCS, Ianhez M, Ramos PM, Miot HA. Prevalence of and risk factors for post-COVID: Results from a survey of 6,958 patients from Brazil. An Acad Bras Cienc. 2023;95(1):e20220143.

Publicado

2023-09-15

Cómo citar

Zambrano-Pico, B., Arteaga-Zambrano, A., Moreira-Mendoza, E., & Castro-Jalca, J. E. (2023). Secuelas comunes en el síndrome post-covid-19: revisión sistemática. MQRInvestigar, 7(3), 4332–4348. https://doi.org/10.56048/MQR20225.7.3.2023.4332-4348

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